Pfizer/BioNTech say updated Covid-19 booster generates 'substantially higher' protection against Omicron subvariants than original vaccine

Pfizer/BioNTech say updated Covid-19 booster generates 'substantially higher' protection against Omicron subvariants than original vaccine

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  • Pfizer and BioNTech said in a news release that the bivalent booster generated about four times higher levels of neutralizing antibody against the Omicron BA.4/BA.5 variants in people older than 55, compared with the original vaccine.
  • “As we head into the holiday season, we hope these updated data will encourage people to seek out a COVID-19 bivalent booster as soon as they are eligible in order to maintain high levels of protection against the widely circulating Omicron BA.4 and BA.5 sublineages,” Pfizer CEO Albert Bourla said in a statement.
  • The companies’ new data comes after two small studies that measured immune responses about three to five weeks after the updated booster dose; both found that the updated Covid-19 booster shots appear to work about as well against the BA.4 and BA.5 Omicron subvariants as the original boosters they replaced.

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