CND Life Sciences' Syn-One Test® Detects Alpha-Synuclein in the Skin with High Sensitivity and Specificity in Patients with Parkinson's Disease and Related Disorders

Key Facts

Data from the NIH-sponsored Synuclein-One Study shows the Syn-One Test® detected phosphorylated alpha-synuclein in skin biopsies of >95% of synucleinopathy patients - The prospective, multicenter, blinded study involved 428 participants across 30 U.S. sites with expert investigators covering movement disorders, dementia, and dysautonomia , /PRNewswire/ -- CND Life Sciences, a medical technology company pioneering the development of cutaneous neurodiagnostics, today announced topline results from its landmark Synuclein-One Study sponsored by the National Institutes of Health (NIH).
This prospective, multicenter study demonstrated that the company's Syn-One Test® detected the pathological form of alpha-synuclein in the skin of over 95% of patients diagnosed with a synucleinopathy, a group of disorders that includes Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and pure autonomic failure.
"With a minimally invasive skin-based test like Syn-One, we can offer our patients a higher degree of confidence and accuracy in the diagnosis of Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, and differentiate these disorders from other neurodegenerative diseases.
About the Synuclein-One Study The Synuclein-One Study is an NIH-funded investigation to determine the accuracy, sensitivity, specificity, and precision of skin biopsy detection of phosphorylated alpha-synuclein in patients clinically diagnosed with a synucleinopathy.