LB Announces Presentation of Full Results of Dopamine Receptor Occupancy Study of LB-102 at the 2021 ACNP Conference

Key Facts

NEW YORK--()--LB Pharmaceuticals Inc, (“LB”) a biotechnology company focused on developing and commercializing novel and improved versions of successful CNS treatments, announced today that the full results of a PET study of LB-102 (a N methylated version of the well-known and highly effective antipsychotic amisulpride), its lead compound to treat schizophrenia, have been presented at the 60th Annual Meeting of the American College of Neuropsychopharmacology (ACNP), held from December 5-8 in San Juan, Puerto Rico.
A double-blind, placebo-controlled, Phase 2 clinical study of LB-102 in schizophrenia patients is expected to begin in the first half of 2022.”
Dean F. Wong, MD, PhD, a Professor of Radiology at Washington University School of Medicine’s Mallinckrodt Institute of Radiology and the principal investigator of the study remarked, “Our observations with LB-102 showed that multiple doses administered once a day resulted in a level of receptor occupancy that previously has been shown with amisulpride to improve symptoms of schizophrenia.
A first-in-human, double-blind, placebo-controlled, Phase 1 clinical of LB-102 study designed to test the safety and pharmacokinetics of LB-102 was completed in 2020, and a second clinical study evaluating dopamine receptor occupancy of LB-102 was completed in 2021.